Apoptosis is also known as programmed cell death. It is involved in cell turnover, embryonic development, immune system function, chemical-induced cell death, and hormone dependent atrophy. Being able to exploit the role of apoptosis in various processes may have critical implications for therapeutic development for several human conditions including neurodegenerative diseases, cancers, and autoimmune disorders.

The pathway below is interactive, meaning you can click on an active pathway component (highlighted in orange) to learn more about available mouse models relevant to that specific gene and pathway function.