PTMs are amino acid side chains modifications that affect some proteins after they are synthesized. There are more than 400 modifications that can affect various protein functions. PTMs play a vital role in biological processes including signal transduction, gene expression, gene activation, DNA repair, and controlling the cell cycle.

The pathway below is interactive, meaning you can click on an active pathway component (highlighted in orange) to learn more about available mouse models relevant to that specific gene and pathway function.