Eukaryotic initiation factor 2 (eIF2) is involved in controlling the initiation of mRNA translation. When its alpha subunit is phosphorylated the initiation phase of protein synthesis is repressed, which allows cells to conserve energy and resources and reduces stress when gene expression begins.

The pathway below is interactive, meaning you can click on an active pathway component (highlighted in orange) to learn more about available mouse models relevant to that specific gene and pathway function.