Protein acetylation is a dynamic and highly specific post-translational modification that influences how proteins function (e.g., gene transcription and signal transduction). The acetylation of proteins is primarily dependent on the enzymes lysine acetyltransferases and lysine deacetylases.

The pathway below is interactive, meaning you can click on an active pathway component (highlighted in orange) to learn more about available mouse models relevant to that specific gene and pathway function.