Metabolism Platform

Bioanalytical Services
Phenotyping Services
Oncology PlatformMetabolism PlatformEfficacy and Pathology Platform
Anti-Tumor Drug Efficacy Evaluation
Patient Derived Xenograft (PDX) Mouse Models and Efficacy ServicesHumanized Immune Checkpoint Mouse Models and Efficacy Services
Non-GLP Toxicity Assessment Services
Metabolic Disease Efficacy Evaluation
Obesity Models and Efficacy ServicesType II Diabetes Models and Efficacy ServiceLiver Disease Models and Efficacy ServicesAtherosclerosis Models and Efficacy ServicesHyperlipidemia Models and Efficacy ServicesGout/Hyperuricemia Models and Efficacy Services
Autoimmune Disease Efficacy Evaluation
Neurodegenerative Disease Efficacy Evaluation
In Vitro TestingIn Vivo Biochemical ExaminingBehavioral AnalysisIn Vivo Drug Efficacy Evaluation
Cell Therapy & Gene Therapy Efficacy Evaluation

GemPharmatech provides animal disease models and genetically humanized models for metabolic diseases, including diabetes mellitus, abnormal lipid metabolism, obesity, and NASH. The company additionally provides a series of in vivo R&D services, with corresponding disease models selected in light of the mechanism of action of the investigational drug.

These models include histopathological analysis, detection of metabolism-related cytokines and inflammatory factors, body weight and food intake, blood glucose, glycosylated haemoglobin (HbA1c), plasma insulin, GTT, and ITT, as well as body composition, bone density, and both indirect and direct metabolic cage tests, which monitor for factors such as CO2  and O2  production, heat, RER and activity, or urine and fecal collection.

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