Infectious Disease Efficacy Evaluation

Mouse models, both wildtype and humanized, can be infected with specific pathogens such as new strains of viruses, drug-resistant bacteria, and invasive fungi, allowing researchers to closely observe pathobiology and immune system responses, leading to the discovery of targeted drugs. In drug development, mouse models allow for the preclinical evaluation of those potential drugs and assessment of their efficacy in reducing pathogen load, alleviating symptoms, and improving survival rates.

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