Reporter Gene Cell Lines

Custom Model Generation Services
Preclinical Testing Services
Bioanalytical ServicesPhenotyping ServicesAnti-Tumor Drug Efficacy EvaluationNon-GLP Toxicity Assessment ServicesMetabolic Disease Efficacy EvaluationAutoimmune Disease Efficacy EvaluationNeurodegenerative Disease Efficacy EvaluationCell Therapy & Gene Therapy Efficacy Evaluation
Germ-Free and Microbiome Services
Mouse-Derived Gut Microbiota LibraryCustomized Germ-free ServicesEvaluation of Anti-tumor Effect of Gut MicrobiotaMicrobiota Extraction and TransplantationGerm-free Rederivation and BreedingMicrobial Strain Culture and Colonization
Cell Lines and Customization Services
Cell Line Customization ServicesSyngeneic Cell LinesReporter Cell LinesCDX Cell Lines
Custom Breeding Services
Customized Mice Breeding ServicesCryopreservation and ResuscitationAssisted ReproductionMouse Rederivation Service
Animal Quality Testing Services
SNP Testing ServicesMicrobiology Testing ServicesGenetic IntegrityAnimal HealthAnimal Welfare
Assay Capabilities
Molecular PlatformPK/PD PlatformPathological Diagnosis PlatformCell-based Service PlatformFlow Cytometry PlatformImaging and Analysis PlatformBehavioral Analysis Platform
NeoMab Fully-Human Antibody Discovery Service
Other Services
Animal Facility and HusbandryReproductive and Embryology Services Isolation of Embryonic Fibroblasts

GemPharmatech has several Luciferase-modified cell lines, comprising solid and hematological malignancies, which provide a wealth of tumor models for evaluating efficacy of new cancer therapies. What's special about these lines? Cell lines that are modified to be tagged with Luciferase allows imaging. That means, as cancer cells metastases/develop across the body, it can be imaged because the luciferase-tag makes it glow under a special machine.


TypesTimes
Humanized tumor cell line customization (One target) + in-vivo mouse tumorigenicity test

3-4 months + 2 months

Gene knockout cell line customization + in-vivo mouse tumorigenicity test

2-3 months + 2 months

Transgene overexpression cell line customization (Including Reporter gene cell lines 

customization) + in-vivo mouse tumorigenicity test

2-3 months + 2 months








Cancer TypeCell LineAvailability
Leukemia

Nalm6-LucAvailable
THP-1-Luc2023 Q1
K562-LucAvailable (Cell only)

Jurkat-Luc

2023 Q1
Liver CancerHuh7-LucAvailable
H22-LucAvailable
HepG2-LucAvailable (Cell only)
Colorectal Cancer HT-29-LucAvailable
HCT116-LucAvailable
Colon CancerRKO-LucAvailable
CT26-LucAvailable (Cell only)
MC38-LucAvailable (Cell only)
Glioblastoma
U251-LucAvailable
U87-LucAvailable
LymphomaRaji-LucAvailable
jeko-1-Luc 2023 Q1
2PK-3-Luc 2023 Q1
U937-LucAvailable
A20-LucAvailable
MOLM13-LucAvailable (Cell only)
Lung Cancer
LLC1-LucAvailable
A549-LucAvailable
Multiple MyelomaRPMI8226-LucAvailable
Mouse Pancreatic CancerKPC-LucAvailable
Bladder CancerMB49-LucAvailable
Skin CancerA375-LucAvailable
Ovarian CancerSKOV3-LucAvailable (Cell only)
Breast Cancer4T1-LucAvailable (Cell only)
MDA-MB-231-LucAvailable (Cell only)
MDA-MB-468-LucAvailable (Cell only)


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