Mouse Rederivation Service

Custom Model Generation Services
Preclinical Testing Services
Bioanalytical ServicesPhenotyping ServicesAnti-Tumor Drug Efficacy EvaluationNon-GLP Toxicity Assessment ServicesMetabolic Disease Efficacy EvaluationAutoimmune Disease Efficacy EvaluationNeurodegenerative Disease Efficacy EvaluationCell Therapy & Gene Therapy Efficacy Evaluation
Germ-Free and Microbiome Services
Mouse-Derived Gut Microbiota LibraryCustomized Germ-free ServicesEvaluation of Anti-tumor Effect of Gut MicrobiotaMicrobiota Extraction and TransplantationGerm-free Rederivation and BreedingMicrobial Strain Culture and Colonization
Cell Lines and Customization Services
Cell Line Customization ServicesSyngeneic Cell LinesReporter Cell LinesCDX Cell Lines
Custom Breeding Services
Customized Mice Breeding ServicesCryopreservation and ResuscitationAssisted ReproductionMouse Rederivation Service
Animal Quality Testing Services
SNP Testing ServicesMicrobiology Testing ServicesGenetic IntegrityAnimal HealthAnimal Welfare
Assay Capabilities
Molecular PlatformPK/PD PlatformPathological Diagnosis PlatformCell-based Service PlatformFlow Cytometry PlatformImaging and Analysis PlatformBehavioral Analysis Platform
NeoMab Fully-Human Antibody Discovery Service
Other Services
Animal Facility and HusbandryReproductive and Embryology Services Isolation of Embryonic Fibroblasts

Mice infected with pathological bacteria, viruses, and internal and external parasites pose a health risk to other animals in the same facility. For animal welfare purposes, taking advantage of the barrier effect of the zona pellucida of fertilized oocytes, embryology techniques such as in vitro fertilization and embryo transfer can be used to remove pathogens and upgrade such colonies to SPF health status. This method of biological purification also can be used to accomplish rapid expansion of the desired mouse strain to match the need of the downstream experiment.


Strengths

  • GemPharmatech has over ten years of experience and expertise in biological purification

  • 3000 batches of biological purification have been completed. 100% success rate in offering at least three SPF offspring with desired genotype.

  • Many rederived offspring have been successfully transferred to the client facility for continued breeding.

  • We provide genotyping service for parental and offspring mice to assure correct identification of the desired offspring.


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