Androgenetic Alopecia (AGA) Models
Androgenetic alopecia, a genetic condition commonly referred to as male-pattern baldness or female-pattern hair loss, is the most prevalent form of hair loss. In males, dihydrotestosterone (DHT), primarily produced from testosterone, attaches to receptors within hair follicles. Over time, this binding causes the follicles to shrink and shortens the hair growth cycle. Consequently, the hair becomes progressively thinner and finer, ultimately ceasing to grow. This typically leads to a receding hairline and balding at the crown. In women, although the underlying mechanism is similar, it usually manifests as diffuse thinning across the scalp rather than complete baldness. Androgenetic alopecia not only impacts physical appearance but can also exert a profound psychological toll on those affected.