Sjögren’ s Syndrome Models

Wild Mouse 750
Wild Mouse 750
Human Xenograft Models
Cell Derived Xenograft Models
Autoimmune Disease Models
Autoimmune Nephropathy modelsAcute Lung Injury ModelsIdiopathic Pulmonary Fibrosis ModelsSjögren’ s Syndrome ModelsSystemic Lupus Erythematosus (SLE) ModelsMultiple Sclerosis ModelsRheumatoid Arthritis ModelsPsoriasis ModelsInflammatory Bowel Disease ModelsAtopic Dermatitis Models Asthma Models
Metabolic Disease Mouse Models
Obesity ModelsDiabetes ModelsMASH ModelsHyperlipidemia ModelsOsteoporosis ModelsHyperuricemia Models
Humanized Immune System Models
huPBMC-NCGhuHSC-NCG-XhuHSC-NCG-hIL15huHSC-NCG
Organs or Tissue Humanized Mouse Models
Wild Mouse 765
Wild Mouse 765
Rare Disease Mouse Models
Progressive Muscular Dystrophy ModelsHemophilia A Models
Neurodegenerative Disease Mouse Models
Alzheimer’s Disease (AD) ModelsParkinson’s Disease (PD) ModelsHuntington's Disease (HD) ModelsAmyotrophic Lateral Sclerosis (ALS) ModelsTransthyretin Amyloidosis (ATTR) Models
Immuno-Oncology Mouse Models
Human Xenograft ModelsHumanized Immune Checkpoint ModelsHumanized Immune System ModelsSpontaneous Tumor Models

Sjögren's syndrome(SS) is an autoimmune disorder that primarily affects the exocrine glands. It particularly targets the salivary and lacrimal glands, resulting in dry mouth (xerostomia) and dry eyes (xerophthalmia). Sjögren's syndrome can also involve other organs and systems, causing various symptoms such as joint pain, fatigue, and difficulties in swallowing.


1. Sjögren’s syndrome model


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Validation data


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Saliva volume decreased in Salivary gland protein induced mice.


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Salivary gland index increased on day63 in salivary gland protein induced mice.

Spleen weight index Increased on day 35 in salivary gland protein induced mice.


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Lymphocytic infiltratio increased in submandibular gland of salivary gland protein induced mice.

CD3+ T cell infiltration increased in submandibular gland of salivary gland protein induced mice.