Cell Therapy and Gene Therapy

Cell Line Engineering
In vitro Pharmacological Evaluation
Antibody Fab Fragment Combination ExperimentADCC Effect Evaluation ExperimentCDC Effect Evaluation ExperimentADCP Effect Evaluation ExperimentImmune Cell Stimulation and Cytokine Release AssayBispecific Antibody T Cell or NK Cell Engager AssayCytokine Neutralization AssayTarget Binding ExperimentsAntibody Internalization AssaysCell Cycle ExperimentsCell Apoptosis ExperimentKilling / Inhibition AssayIn vitro Bystander Effect ExperimentCell Therapy and Gene Therapy
Tumor-bearing Mouse Models

Cell Therapy Drugs


  • Luciferase reporter gene activity-based Cytotoxicity detection

  • Flow cytometryn

  • Cytokine secretion detection


Gene Therapy drugs


Case: In vitro application of primary liver cells from humanized mice for screening small nucleic acid candidate delivery.



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Microscopic examination after 4 hours of cell planking showed a cell convergence rate of 60% to 90% with polygonal, binuclear structures.


Small Molecule Drugs


Cell Killing Experiment


Case: A549 were seeded to a 96-well plate. After cell adhesion, each diluted cisplatin was added. Cell viability was evaluated with CCK8 after 48 hrs.


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Fig. The killing effect of cisplatin on A549 cells in a dose dependent manner  


Cell Scratch Experiment


Cell scratch assay is a widely used method in laboratories for migration assays. The principle behind this method is that when the cells grow and merge into a monolayer, an empty area is intentionally created on this layer, termed a "scratch". Cells at the edge of the scratch will gradually migrate into the void to “heal” or fill the scratch.


Case: A549 cells cultured to 90% confluence in 6-well plates were subjected to scratch assays using a 200μL pipette tip. The cells were then cultured for up to 24 hours under serum-starved conditions, and images were captured to evaluate wound healing.


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Fig. Scratch assay on A549.


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