Killing / Inhibition Assay

Cell Line Engineering
In vitro Pharmacological Evaluation
Antibody Fab Fragment Combination ExperimentADCC Effect Evaluation ExperimentCDC Effect Evaluation ExperimentADCP Effect Evaluation ExperimentImmune Cell Stimulation and Cytokine Release AssayBispecific Antibody T Cell or NK Cell Engager AssayCytokine Neutralization AssayTarget Binding ExperimentsAntibody Internalization AssaysCell Cycle ExperimentsCell Apoptosis ExperimentKilling / Inhibition AssayIn vitro Bystander Effect ExperimentCell Therapy and Gene Therapy
Tumor-bearing Mouse Models

Case: Pharmacological efficacy evaluation of ADC drug DS-8201a (targeting HER2) in vitro.


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Fig. Killing effect of DS-8201a on target cells at different concentrations


GPT Advantages


  • Extensive library of target cells (300+ cancer cell lines and humanized cell lines) in certified BSL-2 level laboratories.

  • Free provision of comparator antibody therapy for common viral infections.

  • Proficiency in Flow Cytometry and molecular analysis platforms.

  • Availability of immune system humanized mice for verifying the Fc effect (ADCC, ADCP, etc.) on ADC drug antibodies, including models like NCG-IL15, NCG-IL2, and NCG-SGM3.

  • Vast project experience.

  • Compliance with regulatory requirements for new drug application submissions.

  • Strict laboratory data storage standards to ensure experiment traceability.


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