In vitro Bystander Effect Experiment

Cell Line Engineering
In vitro Pharmacological Evaluation
Antibody Fab Fragment Combination ExperimentADCC Effect Evaluation ExperimentCDC Effect Evaluation ExperimentADCP Effect Evaluation ExperimentImmune Cell Stimulation and Cytokine Release AssayBispecific Antibody T Cell or NK Cell Engager AssayCytokine Neutralization AssayTarget Binding ExperimentsAntibody Internalization AssaysCell Cycle ExperimentsCell Apoptosis ExperimentKilling / Inhibition AssayIn vitro Bystander Effect ExperimentCell Therapy and Gene Therapy
Tumor-bearing Mouse Models

Case: Pharmacological efficacy evaluation of ADC drug DS-8201a (targeting HER2) in vitro.



图片27.png图片28.png


Fig. Bystander killing assay of DS-8201a


GPT Advantages


  • Extensive library of target cells (300+ cancer cell lines and humanized cell lines) in certified BSL-2 level laboratories.

  • Free provision of comparator antibody therapy for common viral infections.

  • Proficiency in Flow Cytometry and molecular analysis platforms.

  • Availability of immune system humanized mice for verifying the Fc effect (ADCC, ADCP, etc.) on ADC drug antibodies, including models like NCG-IL15, NCG-IL2, and NCG-SGM3.

  • Vast project experience.

  • Compliance with regulatory requirements for new drug application submissions.

  • Strict laboratory data storage standards to ensure experiment traceability.


TALK WITH OUR EXPERTS

GemPharmatech is committed to protecting and respecting your privacy, and we'll only use your personal information to administer your account and to provide the products and services you requested from us. From time to time, we would like to contact you about our products and services, as well as other content that may be of interest to you. If you consent to us contacting you for this purpose, please click below to say how you would like us to contact you:

In order to provide you with the content requested, we need to store and process your personal data. If you consent to us storing your personal data for this purpose, please click the checkbox below.

You can unsubscribe from these communications at any time. For more information on how to unsubscribe, our privacy practices, and how we are committed to protecting and respecting your privacy, please review our Privacy Policy.