Target Binding Experiments

Cell Line Engineering
In vitro Pharmacological Evaluation
Antibody Fab Fragment Combination ExperimentADCC Effect Evaluation ExperimentCDC Effect Evaluation ExperimentADCP Effect Evaluation ExperimentImmune Cell Stimulation and Cytokine Release AssayBispecific Antibody T Cell or NK Cell Engager AssayCytokine Neutralization AssayTarget Binding ExperimentsAntibody Internalization AssaysCell Cycle ExperimentsCell Apoptosis ExperimentKilling / Inhibition AssayIn vitro Bystander Effect ExperimentCell Therapy and Gene Therapy
Tumor-bearing Mouse Models

Case: In vitro pharmacological efficacy assay of DS-8201a (an ADC drug targeting HER2). 


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Fig. Binding assay of DS-8201a in different cancer cell lines


GPT Advantages


  • Extensive library of target cells (300+ cancer cell lines and humanized cell lines) and certified BSL-2 level laboratories.

  • Free provision of comparator antibody therapy for common viral infections.

  • Proficient in Flow Cytometry and molecular analysis platforms.

  • Immune system humanized mice available for functional verification of Fc effects (ADCC, ADCP, etc.) on ADC drug antibodies, including NCG-IL15, NCG-IL2, and NCG-SGM3 models.

  • Vast project experience.

  • Compliance with regulatory requirements for new drug application submissions.

  • Strict laboratory data storage standards ensure experiment traceability.


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