45% HFHSD Induced Obesity(DIO) models
Study Outline
Figure 1. HFD: 60% high-fat diet; HFHSD: 45% high-fat, high-sugar diet. Experimental period: 12-20 weeks.
Data validation
1. Body weight curve
Figure 2. The body weight of C57BL/6 mice increased significantly after feeding with 45% HFHSD.Data are presented as Mean±SD.*, p<0.05;**, p<0.01;***, p<0.001 by unpaired two-tailed Student's t-test.
2. Postprandial blood glucose
Figure 3. The postprandial blood glucose of C57BL/6 mice increased significantly after feeding with 45% HFHSD for 8 weeks. Data are presented as Mean±SD.**, p<0.01; by unpaired two-tailed Student's t-test.
3. Blood lipid levels
Figure 4. The plasma cholesterol and triglyceride levels of C57BL/6 mice increased significantly after feeding with 45% HFHSD for 8 weeks. Data are presented as Mean±SD.***, p<0.001****, p<0.0001 by unpaired two-tailed Student's t-test.