An immunodeficient mouse is one which has deficiencies in one or more components of the immune system. With the advent of gene editing technology, more and more immunodeficienct mouse strains have been developed, playing an increasingly important role in the research fields of immunology, infectious diseases, oncology, and stem cell biology. In addition to our NCG and NCG derivative lines, GemPharmatech offers a number of other immunodecifient strains.
|Strain Name||Strain Type||Description|
|D000521||BALB/c-Nude||Spontaneous Mutation||Lack of T cells|
|T004753||B6-Rag1-KO||Cas9-KO||Lack of T/B cells|
|T015768||B6-Il2rg-KO||Cas9-KO||Lack of NK cells|
|T002289||NOD/ShiLtJGpt-Rag1/Il2rg-KO||Cas9-KO||Lack of T/B/NK cells|
|T001492||NOD-Scid||Cas9-KO||Lack of T/B cells|