Antibody Binding Assay

Molecular Platform
PK/PD Platform
Pathological Diagnosis Platform
Cell-based Service Platform
Cell Line Engineering In vitro Pharmacological EvaluationTumor-bearing Mouse Models
Flow Cytometry Platform
Services and AdvantagesImmune Cell ProfilingTumor Infiltrating Lymphocyte (TILs) DetectionRed Blood Cell and Platelet DetectionTissue Sample AnalysisAntibody Binding AssayCytometric Bead Array
Imaging and Analysis Platform
Behavioral Analysis Platform

The antibody binding assay evaluates the binding between antibody-based drugs and target-positive cells, target-humanized mouse cells, or target-modified mouse cells. It determines the EC50 of the drug and provides a reference for in vivo efficacy by comparing it with positive control drugs.


Experimental Case Study: Analyzing the binding activity of target-modified cells with different concentrations of Opdivo and Keytruda.


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Advantages


  • Familiar with the regulatory requirements for new drug submissions.

  • Extensive repository of target cells (150+ CDX cell lines and humanized engineered mice cell lines).

  • Provision of common target-positive antibody drugs as controls for free.


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