In the case of antibacterial and antifungal drug screening, we offer comprehensive services. For bacteria, we can determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of drugs. The Time-Kill Kinetics Assay helps understand the speed of drug action, and Antibiotic Combination Testing evaluates interactions between different antibiotics. For fungi, we can precisely assess the impact of drugs on fungal growth and survival.
Bacteria and fungu culture
● Minimum Inhibitory Concentration (MIC) Determination
MIC is the lowest concentration of an antibacterial agent that inhibits the visible growth of bacteria. We use methods such as broth dilution, agar dilution, and E-test to accurately determine the MIC of various antibacterial drugs against different bacterial strains. This information is crucial for clinicians to select the most appropriate antibiotic for treatment and for researchers to evaluate the potency of new antibacterial compounds.
● Minimum Bactericidal Concentration (MBC) Determination
MBC is the lowest concentration of an antibacterial agent that kills bacteria. In addition to determining the MIC, we can further conduct experiments to find the MBC. By subculturing bacteria from MIC test wells or plates onto fresh media, we can identify the concentration at which no viable bacteria are able to grow. This helps in understanding whether a drug is bacteriostatic (inhibits growth) or bactericidal (kills bacteria), which is important for choosing the right treatment strategy.