Cell Lines Resources

GemPharmatech maintains a comprehensive collection of well-characterized cell line resources, including murine-derived cell lines, genetically engineered mouse models with humanized target modifications, and human tumor cell lines, which are readily available to support various pharmacodynamic evaluations and oncology-related research applications.

  • Cell Type Name
    CT26-mSTK11(KO)
  • Disease Type
    Colon Cancer
  • Cell Type
    Human Target-Modified Cell
  • Species Origin
    Mus musculus
  • Host Mouse
    BALB/c-hPD1

1. Detection of Cell Target Expression

Western blot was used to detect the expression level of mSTK11 protein in CT26-mSTK11(KO) cells, with results shown below:


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Figure 1 Expression level of mSTK11 protein in CT26-mSTK11(KO) cells


2. Tumor Formation Validation Data

CT26-mSTK11(KO) can form tumors normally after subcutaneous inoculation in BALB/c-hPD1( T002726), with data as follows:


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Figure 2 (A) Tumor growth curve of CT26-mSTK11(KO) in BALB/c-hPD1 subcutaneous inoculation model;

(B) Body weight changes of mice in CT26-mSTK11(KO) BALB/c-hPD1 subcutaneous inoculation model (n=6)