C57BL/6JGpt (Aged mice)

Model: C57BL/6JGpt (Aged mice)
Strain Number: T065274

Inbred strain

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt (Aged mice)
Strain Number: T065274
Official Symbol: /
Strain Strategy: T065274.C57BL_6JGpt (Aged mice) strain info.pdf
NCBI Number: /
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Inbred strain
Inventory Status: Live
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Increased reactive astrocytes in hippocampal CA1 region mediated by decreased CXCR7 is involved in postoperative cognitive dysfunction in aged mice. Cell biology and toxicology (2025)2. Sarcosine decreases in sarcopenia and enhances muscle regeneration and adipose thermogenesis by activating anti-inflammatory macrophages. Nature aging (2025)3. Increased SOAT2 expression in aged regulatory T cells is associated with altered cholesterol metabolism and reduced anti-tumor immunity. Nature communications (2025)4. CircXYLT1 suppresses oxidative stress and promotes vascular remodeling in aging mice carotid artery injury model of atherosclerosis via PTBP1. Experimental gerontology (2025)5. BM-MSC-derived migrasomes reverse stroke-induced thymic atrophy and immunosuppression via Pin1 delivery to thymic epithelial cells. Journal of neuroinflammation (2025)6. Oral Delivery of R-spondin1-Loaded Small Extracellular Vesicles Activates WNT Signalling Pathway to Accelerate Intestinal Injury Repair and Reverse Ageing. Journal of extracellular vesicles (2026)7. Aged Small Intestine Derived Small Extracellular Vesicles miR-214-3p Leads to Intermuscular Fatty Infiltration Through Wnt/β-Catenin Mediated Fibro-Adipogenic Progenitors Adipogenesis. FASEB J (2026)

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.