BALB/cJGpt-Nlrp3em7Cd16453/Gpt

Mouse Model: Nlrp3-KO
Strain Number: T056237

Knockout (KO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: BALB/cJGpt-Nlrp3em7Cd16453/Gpt
Strain Number: T056237
Official Symbol: Nlrp3
Strain Strategy: T056237.Nlrp3 Cas9-KO Strategy-EN(BALBcJGpt)-20211119.pdf
Official Full Name: NLR family, pyrin domain containing 3
Also Known As: FCU,MWS,FCAS,Cias1,Mmig1,NALP3,Pypaf1,AII/AVP,AGTAVPRL
NCBI Number: 216799
MGI Number: 2653833
Chromosome: 11
Deletion (size): -16453bp
Research Areas: Metabolic research,Protein metabolism,homeostasis/metabolism,Developmental Biology,cell differentiation,growth/size/body,nervous system,Physiological system,integument,reproductive system,digestive/alimentary system,liver/biliary system,Cell biology,Cell death,cellular,Cell localization,endoplasmic reticulum,cell nucleus,Molecular biology,DNA binding protein
Strain Background: [N000020] BALB/cJGpt
Modification Type: Knockout (KO)
Genotyping Protocols: T056237.Nlrp3 Genotyping Protocol(KO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. NLRP3 inflammasome-modulated angiogenic function of EPC via PI3K/Akt/mTOR pathway in diabetic myocardial infarction. Cardiovascular diabetology (2025)
Gene Family: NLR familyPyrin domain containing

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.