Hot Search:

C57BL/6JGpt-Ptprcem1Cin(p.K302E)/Gpt (Academic Research)

Mouse Model: B6-CD45.1
Strain Number: T054816

Point mutation (PM)

  • Product Type:
  • Quantity: - +
  • Sex:
  • Age:
  • Genotype:

GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Ptprcem1Cin(p.K302E)/Gpt (Academic Research)
Strain Number: T054816
Official Symbol: Ptprc
Strain Strategy: T054816.B6JGpt-CD45.1 strain info.pdf
Official Full Name: protein tyrosine phosphatase,receptor type,C
Also Known As: loc,B220,Cd45,L-CA,Ly-5,T200,CD45R
NCBI Number: 19264
MGI Number: 97810
Chromosome: 1
Research Areas: Disease Models,Rare disease
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Point mutation (PM)
Inventory Status: Live,Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Efficient expansion of mouse hematopoietic stem cells ex vivo by membrane anchored Angptl2. Biochem Biophys Res Commun (2022)2. A lncRNA from an inflammatory bowel disease risk locus maintains intestinal host-commensal homeostasis. Cell Res (2023)3. B cell subsets contribute to myocardial protection by inducing neutrophil apoptosis after ischemia and reperfusion. JCI Insight (2024)4. Megakaryocytic IGF1 coordinates activation and ferroptosis to safeguard hematopoietic stem cell regeneration after radiation injury. Cell Commun Signal (2024)5. Crystalline silica-induced recruitment and immuno-imbalance of CD4(+) tissue resident memory T cells promote silicosis progression. Commun Biol (2024)6. Mechanics-activated fibroblasts promote pulmonary group 2 innate lymphoid cell plasticity propelling silicosis progression. Nat Commun (2024)7. Circadian Rhythm Disruption Exacerbates Autoimmune Uveitis: The Essential Role of PER1 in Treg Cell Metabolic Support for Stability and Function. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2025)
Gene Family: CD moleculesFibronectin type III domain containingProtein tyrosine phosphatases receptor type

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.

Learn More About Our Research Services Learn More