C57BL/6JGpt-Tg(hSNCA-A53T)62/Gpt
B6-hSNCA-A53T|Strain NO.T054329
Transgenic (Tg)
- Product Type:
- Quantity: - +
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BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Tg(hSNCA-A53T)62/Gpt |
| Strain Number: | T054329 |
| Official Symbol: | Snca |
| Strain Strategy: | T054329.B6-hSNCA A53T strain info.pdf |
| Official Full Name: | synuclein alpha,synuclein, alpha |
| Also Known As: | NACP,alpha-Syn,alphaSYN |
| NCBI Number: | 20617 |
| MGI Number: | 1277151 |
| Chromosome: | 6 |
| Research Areas: | Disease Models,Neurodegenerative diseases,Parkinson's disease |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Transgenic (Tg) |
| Inventory Status: | Live,Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Plasminogen degrades alpha-synuclein, Tau and TDP-43 and decreases dopaminergic neurodegeneration in mouse models of Parkinson's disease. Sci Rep (2024)2. Activated TBK1 promotes ACSL1-mediated microglia lipid droplet accumulation and neuroinflammation in Parkinson's disease. Journal of neuroinflammation (2025)3. YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM2. Clinical and translational medicine (2025) |