C57BL/6JGpt-Tg(Thy-APP/Thy-PSEN1)5/Gpt
FAD4T|Strain NO.T053302
Transgenic (Tg)
- Product Type:
- Quantity: - +
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- Age:
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BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Tg(Thy-APP/Thy-PSEN1)5/Gpt |
| Strain Number: | T053302 |
| Official Symbol: | APP,PSEN1 |
| Strain Strategy: | T053302.FAD 4T strain info.pdf |
| Official Full Name: | amyloid beta precursor protein,presenilin 1 |
| Also Known As: | AAA,ABETA,ABPP,AD1,APPI,CTFgamma,CVAP,PN-II,PN2,alpha-sAPP,preA4 |
| NCBI Number: | 3515663 |
| Research Areas: | Disease Models,Neurodegenerative diseases,Alzheimer's disease |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Transgenic (Tg) |
| Inventory Status: | Live,Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Pathological BBB Crossing Melanin-Like Nanoparticles as Metal-Ion Chelators and Neuroinflammation Regulators against Alzheimer's Disease2. H3K18 lactylation of senescent microglia potentiates brain aging and Alzheimer's disease through the NFkappaB signaling pathway3. Targeting aberrant glycosylation to modulate microglial response and improve cognition in models of Alzheimer's disease |