C57BL/6JGpt-Npc1em28Cd2284/Gpt

Npc1-KO|Strain NO.T052870

Knockout (KO)

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BASIC INFORMATION
Strain Name: C57BL/6JGpt-Npc1em28Cd2284/Gpt
Strain Number: T052870
Official Symbol: Npc1
Strain Strategy: T052870.Npc1 Cas9-KO Strategy-EN.pdfT052870. Npc1-KO strain info.pdf
Official Full Name: NPC intracellular cholesterol transporter 1
Also Known As: A430089E03Rik,C85354,D18Ertd139e,D18Ertd723e,lcsd,nmf164,spm
NCBI Number: 1097712
Deletion (size): -2284bp
Research Areas: Metabolic research,adipose tissue,Protein metabolism,Glucose metabolism,homeostasis/metabolism,Lipid Metabolism,Developmental Biology,growth/size/body,mortality/aging,immune system,nervous system,vision/eye,taste/olfaction,behavior/neurological,Physiological system,integument,cardiovascular system,skeleton,craniofacial ,respiratory system,reproductive system,digestive/alimentary system,liver/biliary system,endocrine/exocrine glands,hematopoietic system,Cell biology,Cell death,cellular,Cell localization,Cytoplasmic vesicle,endoplasmic reticulum,endosome,Golgi apparatus,cell nucleus,cytomembrane,Organelles membrane,Molecular biology,Lipid binding protein,transporter,Niemann-Pick Disease
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockout (KO)
Genotyping Protocols: T052870.Npc1 Genotyping Protocol(KO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. EXTL3 and NPC1 are mammalian host factors for Autographa californica multiple nucleopolyhedrovirus infection. Nature Communications (2024)