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C57BL/6JGpt-Lyz2em1Cin(CreERT2)/Gpt

Lyz2-CreERT2|Strain NO.T052789

Knockin (KI)

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BASIC INFORMATION
Strain Name: C57BL/6JGpt-Lyz2em1Cin(CreERT2)/Gpt
Strain Number: T052789
Official Symbol: Lyz2,CreERT2
Strain Strategy: T052789.Lyz2-CreERT2 Cas9-KI Strategy-EN.pdfT052789.Lyz2-CreERT2 strain info.pdf
Official Full Name: lysozyme 2
Also Known As: AI326280,Lys,Lysm,Lyzf2,Lyzs,Lzm,Lzm-s1,Lzp
NCBI Number: 17105
MGI Number: 96897
Chromosome: 10
Research Areas: Tool Mice,Cre/Dre
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockin (KI)
Genotyping Protocols: T052789.Lyz2-CreERT2 Genotyping Protocol(KI).pdf
Inventory Status: Live,Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Palmitic acid in type 2 diabetes mellitus promotes atherosclerotic plaque vulnerability via macrophage Dll4 signaling. Nat Commun (2024)2. SIRT1 mediates the inflammatory response of macrophages and regulates the TIMP3/ADAM17 pathway in atherosclerosis. Experimental Cell Research (2024)3. Nonenzymatic lysine d-lactylation induced by glyoxalase II substrate SLG dampens inflammatory immune responses. Cell research (2025)4. Resistance to anti-LAG-3 plus anti-PD-1 therapy in head and neck cancer is mediated by Sox9+ tumor cells interaction with Fpr1+ neutrophils. Nat Commun (2025)5. Hexosamine biosynthesis dysfunction-induced LIFR N-glycosylation deficiency exacerbates steatotic liver ischemia/reperfusion injury. Metabolism (2025)