C57BL/6JGpt-Sirt1em1Cflox/Gpt
Sirt1-flox|Strain NO.T052096
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
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BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Sirt1em1Cflox/Gpt |
| Strain Number: | T052096 |
| Official Symbol: | Sirt1 |
| Strain Strategy: | T052096.Sirt1 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | sirtuin 1 |
| Also Known As: | AA673258,SIR2L1,Sir2,Sir2a,Sir2alpha |
| NCBI Number: | 93759 |
| MGI Number: | 2135607 |
| Chromosome: | 10 |
| Distance Between Two Loxps: | 2170bp |
| Research Areas: | Metabolic research,Developmental Biology,immune system,integument,cardiovascular system,nervous system,Signal Transduction,skeleton,vision/eye,Muscle ,respiratory system,adipose tissue,Cell Proliferation,Cell death,DNA transcription,reproductive system,digestive/alimentary system,Protein metabolism,liver/biliary system,renal/urinary system,Mitochondrial research,Physiological system,endocrine/exocrine glands,homeostasis/metabolism,behavior/neurological,cell differentiation,Cell biology,Molecular biology,cellular,craniofacial ,embryo,growth/size/body,hematopoietic system,limbs/digits/tail,mortality/aging,Cell localization,Lipid Metabolism,cell nucleus,cytomembrane,DNA binding protein,hydrolytic enzyme,transferase |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T052096.Sirt1 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. SIRT1 mediates the inflammatory response of macrophages and regulates the TIMP3/ADAM17 pathway in atherosclerosis |
| Gene Family: | eNoSC complexSirtuins |