C57BL/6JGpt-Il1r1em1Cflox/Gpt
Il1r1-flox|Strain NO.T051929
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
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BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Il1r1em1Cflox/Gpt |
| Strain Number: | T051929 |
| Official Symbol: | Il1r1 |
| Strain Strategy: | T051929.Il1r1 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | interleukin 1 receptor,type I |
| Also Known As: | CD121a,CD121b,IL-1R1,IL-iR,Il1r-1 |
| NCBI Number: | 16177 |
| MGI Number: | 96545 |
| Chromosome: | 1 |
| Distance Between Two Loxps: | 9537bp |
| Research Areas: | Metabolic research,adipose tissue,homeostasis/metabolism,Developmental Biology,cell differentiation,growth/size/body,mortality/aging,immune system,Tumor research,nervous system,behavior/neurological,synapse,Physiological system,cardiovascular system,skeleton,craniofacial ,digestive/alimentary system,liver/biliary system,renal/urinary system,hematopoietic system,Cell biology,cellular,cell nucleus,Organelles membrane,Molecular biology,Signal Transduction,hydrolytic enzyme |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T051929.Il1r1 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Conditional Knockout of IL-1R1 in Endothelial Cells Attenuates Seizures and Neurodegeneration via Inhibiting Neuroinflammation Mediated by Nrf2/HO-1/NLRP3 Signaling in Status Epilepticus Model2. Conditional Knockout of IL-1R1 in Endothelial Cells Attenuates Seizures and Neurodegeneration via Inhibiting Neuroinflammation Mediated by Nrf2/HO-1/NLRP3 Signaling in Status Epilepticus Model |
| Gene Family: | CD moleculesI-set domain containingInterleukin receptorsTIR domain containing |