C57BL/6JGpt-Tlr4em26Cd1829/Gpt
Tlr4-KO|Strain NO.T051714
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Tlr4em26Cd1829/Gpt |
| Strain Number: | T051714 |
| Official Symbol: | Tlr4 |
| Strain Strategy: | T051714.Tlr4 Cas9-KO Strategy-EN.pdf |
| Official Full Name: | toll-like receptor 4 |
| Also Known As: | Lps,Ly87,Ran/M1,Rasl2-8 |
| NCBI Number: | 21898 |
| MGI Number: | 96824 |
| Chromosome: | 4 |
| Deletion (size): | -1829bp |
| Research Areas: | Metabolic research,adipose tissue,Protein metabolism,homeostasis/metabolism,Developmental Biology,cell differentiation,growth/size/body,mortality/aging,immune system,Tumor research,nervous system,vision/eye,behavior/neurological,Physiological system,integument,pigmentation,cardiovascular system,skeleton,Muscle ,respiratory system,reproductive system,digestive/alimentary system,liver/biliary system,renal/urinary system,hematopoietic system,Cell biology,Cell Proliferation,Cell death,cellular,Cell localization,Cytoplasmic vesicle,endosome,Golgi apparatus,Organelles membrane,Molecular biology,Signal Transduction,DNA transcription,hydrolytic enzyme,Lipid binding protein |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T051714.Tlr4 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis2. Inhibition of Hyperglycemia and Hyperlipidemia by Blocking Toll-like Receptor 4: Comparison of Wild-Type and Toll-like Receptor 4 Gene Knockout Mice on Obesity and Diabetes Modeling |
| Gene Family: | CD moleculesToll like receptors |