C57BL/6JGpt-Gpx4em2Cflox/Gpt
Gpx4-flox|Strain NO.T050827
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Gpx4em2Cflox/Gpt |
| Strain Number: | T050827 |
| Official Symbol: | Gpx4 |
| Strain Strategy: | T050827.Gpx4 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | glutathione peroxidase 4 |
| Also Known As: | GPx-4,GSHPx-4,mtPHGPx,snGPx |
| NCBI Number: | 625249 |
| MGI Number: | 104767 |
| Chromosome: | 10 |
| Distance Between Two Loxps: | 11411bp |
| Research Areas: | Metabolic research,homeostasis/metabolism,Developmental Biology,embryo,growth/size/body,mortality/aging,nervous system,behavior/neurological,Physiological system,cardiovascular system,reproductive system,digestive/alimentary system,liver/biliary system,Cell biology,Cell death,Mitochondrial research,cellular,cell nucleus,Organelles membrane,Molecular biology,oxidordeuctase |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T050827.Gpx4 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. DNA Methylation-Mediated GPX4 Transcriptional Repression and Osteoblast Ferroptosis Promote Titanium Particle-Induced Osteolysis |
| Gene Family: | Selenoproteins |