C57BL/6JGpt-Usp11em15Cd3314/Gpt

Mouse Model: Usp11-KO
Strain Number: T050694

Knockout (KO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Usp11em15Cd3314/Gpt
Strain Number: T050694
Official Symbol: Usp11
Strain Strategy: T050694.Usp11 Cas9-KO Strategy-EN.pdf
Official Full Name: ubiquitin specific peptidase 11
Also Known As: mKIAA4085,6230415D12Rik
NCBI Number: 236733
MGI Number: 2384312
Chromosome: X
Deletion (size): -3314bp
Research Areas: Metabolic research,Protein metabolism,homeostasis/metabolism,immune system,Physiological system,reproductive system,endocrine/exocrine glands,hematopoietic system,Cell biology,cellular,cell nucleus,Molecular biology,hydrolytic enzyme
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockout (KO)
Genotyping Protocols: T050694.Usp11 Genotyping Protocol(KO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. USP11 Exacerbates Radiation-Induced Pneumonitis by Activating Endothelial Cell Inflammatory Response via OTUD5-STING Signaling. Int J Radiat Oncol Biol Phys (2024)
Gene Family: Ubiquitin specific peptidases

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.