C57BL/6JGpt-Gper1em5Cd4065/Gpt
Gper1-KO|Strain NO.T050292
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Gper1em5Cd4065/Gpt |
| Strain Number: | T050292 |
| Official Symbol: | Gper1 |
| Strain Strategy: | T050292.Gper1 Cas9-KO Strategy-EN.pdf |
| Official Full Name: | G protein-coupled estrogen receptor 1 |
| Also Known As: | 6330420K13Rik,CMKRL2,Ceprl,FEG-1,GPCR-Br,Gper,Gpr30 |
| NCBI Number: | 76854 |
| MGI Number: | 1924104 |
| Chromosome: | 5 |
| Deletion (size): | -4065bp |
| Research Areas: | Metabolic research,Protein metabolism,homeostasis/metabolism,Lipid Metabolism,Developmental Biology,cell differentiation,growth/size/body,immune system,nervous system,synapse,Physiological system,cardiovascular system,skeleton,digestive/alimentary system,liver/biliary system,endocrine/exocrine glands,hematopoietic system,limbs/digits/tail,Cell biology,Cell Proliferation,Cell death,Cytoskeleton,Mitochondrial research,cellular,Cell localization,Cytoplasmic vesicle,endoplasmic reticulum,endosome,Golgi apparatus,cell nucleus,cytomembrane,Organelles membrane,Molecular biology,Signal Transduction,DNA transcription,Lipid binding protein |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T050292.Gper1 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Estradiol mitigates stress-induced cardiac injury and inflammation by downregulating ADAM17 via the GPER-1/PI3K signaling pathway. Cell Mol Life Sci (2023)2. Modulation of GPER1 alleviates early brain injury via inhibition of A1 reactive astrocytes activation after intracerebral hemorrhage in mice. Heliyon (2024) |
| Gene Family: | G protein-coupled estrogen receptor |