C57BL/6JGpt-Igf2em1Cflox/Gpt

Mouse Model: Igf2-flox
Strain Number: T016231

Conditional knockout (cKO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Igf2em1Cflox/Gpt
Strain Number: T016231
Official Symbol: Igf2
Strain Strategy: T016231.Igf2 Cas9-CKO Strategy-EN.pdf
Official Full Name: insulin-like growth factor 2
Also Known As: AL033362,Igf-2,Igf-II,M6pr,Mpr,Peg2
NCBI Number: 16002
MGI Number: 96434
Chromosome: 7
Distance Between Two Loxps: 4969bp
Research Areas: Metabolic research,Developmental Biology,immune system,cardiovascular system,nervous system,Signal Transduction,skeleton,vision/eye,Muscle ,Cell Proliferation,DNA transcription,digestive/alimentary system,Protein metabolism,liver/biliary system,renal/urinary system,Physiological system,endocrine/exocrine glands,homeostasis/metabolism,cell differentiation,Cell biology,Molecular biology,cellular,embryo,growth/size/body,hematopoietic system,limbs/digits/tail,mortality/aging,Lipid Metabolism,Regulation of enzyme activity
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Conditional knockout (cKO)
Genotyping Protocols: T016231.Igf2 Genotyping Protocol(CKO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Insulin-Like Growth Factor 2 Reverses Synaptic and Cognitive Deficits in Fetal Growth Restriction Mice. FASEB J (2025)
Gene Family: MicroRNA protein coding host genesNeuropeptides

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.