C57BL/6JGpt-Trex1em1Cd1194/Gpt
Mouse Model: Trex1-KO
Strain Number: T013987
Knockout (KO)
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- Quantity: - +
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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library
With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
| Strain Name: | C57BL/6JGpt-Trex1em1Cd1194/Gpt |
| Strain Number: | T013987 |
| Official Symbol: | Trex1 |
| Strain Strategy: | Log in to read more |
| Official Full Name: | three prime repair exonuclease 1 |
| Also Known As: | AU041952 |
| NCBI Number: | 22040 |
| MGI Number: | 1328317 |
| Chromosome: | 9 |
| Deletion (size): | -1194bp |
| Research Areas: | Disease Models,Autoimmune diseases,Systemic lupus erythematosus |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Inventory Status: | Live,Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Stress granule-localized USP8 potentiates cGAS-mediated type I interferonopathies through deubiquitination of DDX3X. Cell Rep (2024)2. USP29 maintains the stability of cGAS and promotes cellular antiviral responses and autoimmunity. Cell research (2020) |
| Gene Family: | ExonucleasesSET complex |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.