C57BL/6JGpt-Gnasem17Cd70423/Gpt

Model: Gnas-KO
Strain Number: T012651

Knockout (KO)

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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library

With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.

BASIC INFORMATION
Strain Name: C57BL/6JGpt-Gnasem17Cd70423/Gpt
Strain Number: T012651
Official Symbol: Gnas
Strain Strategy: T012651.Gnas Cas9-KO Strategy-EN(1).pdf
Official Full Name: GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
Also Known As: 5530400H20Rik,A930027G11Rik,C130027O20Rik,GPSA,GSP,Galphas,Gnas1,Gnasxl,Gs-alpha,Gsa,Nesp,Nesp55,Nespl,Oed-Sml,Oedsml,P1,P2,P3,PHP1A,PHP1B,POH,SCG6
NCBI Number: 14683
MGI Number: 95777
Chromosome: 2
Deletion (size): -70423bp
Research Areas: Metabolic research,adipose tissue,Protein metabolism,homeostasis/metabolism,Developmental Biology,cell differentiation,growth/size/body,mortality/aging,immune system,nervous system,hearing/ear,behavior/neurological,Physiological system,integument,cardiovascular system,skeleton,craniofacial ,Muscle ,respiratory system,digestive/alimentary system,liver/biliary system,renal/urinary system,endocrine/exocrine glands,hematopoietic system,limbs/digits/tail,Cell biology,Cell Proliferation,cellular,Cell localization,Cytoplasmic vesicle,endosome,Golgi apparatus,cell nucleus,Organelles membrane,Molecular biology,Signal Transduction,DNA transcription,Regulation of enzyme activity,hydrolytic enzyme,McCune-Albright Syndrome
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockout (KO)
Genotyping Protocols: T012651.Gnas Genotyping Protocol(KO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Gene Family: G protein subunits alpha, group sGranins

Extend the Value of Your Mouse Models with Integrated Preclinical Services

GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.