C57BL/6JGpt-Rag2em6Cd6972/Gpt
Mouse Model: Rag2-KO
Strain Number: T011534
Knockout (KO)
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- Quantity: - +
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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library
With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
| Strain Name: | C57BL/6JGpt-Rag2em6Cd6972/Gpt |
| Strain Number: | T011534 |
| Official Symbol: | Rag2 |
| Strain Strategy: | T011534.Rag2 Cas9-KO Strategy-EN.pdfT011534.Rag2-KO strain info.pdf |
| Official Full Name: | recombination activating gene 2 |
| Also Known As: | Rag-2 |
| NCBI Number: | 19374 |
| MGI Number: | 97849 |
| Chromosome: | 2 |
| Deletion (size): | -6972bp |
| Research Areas: | Developmental Biology,cell differentiation,growth/size/body,mortality/aging,immune system,Physiological system,integument,respiratory system,digestive/alimentary system,endocrine/exocrine glands,hematopoietic system,Cell biology,Cell Proliferation,cellular,cell nucleus,Molecular biology,DNA binding protein,Lipid binding protein,Primary Combined Immune Deficiency |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T011534.Rag2 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Elevated nitric oxide during colitis restrains GM-CSF production in ILC3 cells via suppressing an AhR-Cyp4f13-NF-κB axis. Nature communications (2025)2. Gasdermin-D-mediated epithelial-immune circuit synchronizes nutrient absorption and host defense in the small intestine. Immunity (2025) |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.