C57BL/6JGpt-Rag2em6Cd6972/Gpt
Rag2-KO|Strain NO.T011534
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Rag2em6Cd6972/Gpt |
| Strain Number: | T011534 |
| Official Symbol: | Rag2 |
| Strain Strategy: | T011534.Rag2 Cas9-KO Strategy-EN.pdfT011534.Rag2-KO strain info.pdf |
| Official Full Name: | recombination activating gene 2 |
| Also Known As: | Rag-2 |
| NCBI Number: | 19374 |
| MGI Number: | 97849 |
| Chromosome: | 2 |
| Deletion (size): | -6972bp |
| Research Areas: | Developmental Biology,cell differentiation,growth/size/body,mortality/aging,immune system,Physiological system,integument,respiratory system,digestive/alimentary system,endocrine/exocrine glands,hematopoietic system,Cell biology,Cell Proliferation,cellular,cell nucleus,Molecular biology,DNA binding protein,Lipid binding protein,Primary Combined Immune Deficiency |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T011534.Rag2 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Elevated nitric oxide during colitis restrains GM-CSF production in ILC3 cells via suppressing an AhR-Cyp4f13-NF-κB axis. Nature communications (2025)2. Gasdermin-D-mediated epithelial-immune circuit synchronizes nutrient absorption and host defense in the small intestine. Immunity (2025) |