C57BL/6JGpt-Smpdl3aem1Cd11362/Gpt

Smpdl3a-KO|Strain NO.T031526

Knockout (KO)

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BASIC INFORMATION
Strain Name: C57BL/6JGpt-Smpdl3aem1Cd11362/Gpt
Strain Number: T031526
Official Symbol: Smpdl3a
Strain Strategy: T031526.Smpdl3a Cas9-KO Strategy-EN.pdf
Official Full Name: sphingomyelin phosphodiesterase, acid-like 3A
Also Known As: 0610010C24Rik,AI529588,ASM3A,ASML3,ASML3A
NCBI Number: 57319
MGI Number: 1931437
Chromosome: 10
Deletion (size): -11362bp
Research Areas: Metabolic research,homeostasis/metabolism,Lipid Metabolism,Physiological system,integument,Molecular biology,hydrolytic enzyme
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockout (KO)
Genotyping Protocols: T031526.Smpdl3a Genotyping Protocol(KO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing. Immunity (2023)