C57BL/6JGpt-Mrgprb2em18Cd4315/Gpt
Mrgprb2-KO|Strain NO.T009034
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Mrgprb2em18Cd4315/Gpt |
| Strain Number: | T009034 |
| Official Symbol: | Mrgprb2 |
| Strain Strategy: | T009034.Mrgprb2 Cas9-KO Strategy-EN.pdf |
| Official Full Name: | MAS-related GPR, member B2 |
| Also Known As: | 4833406I20Rik,Mgrg14 |
| NCBI Number: | 243979 |
| MGI Number: | 2441674 |
| Chromosome: | 7 |
| Deletion (size): | -4315bp |
| Research Areas: | immune system,Inflammation,nervous system,vision/eye,behavior/neurological,Physiological system,integument,hematopoietic system,Cell biology,Organelles membrane,Molecular biology,Signal Transduction |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T009034.Mrgprb2 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Colitis aggravated by Mrgprb2 knockout is associated with altered immune response, intestinal barrier function and gut microbiota. Exp Physiol (2023)2. Mrgprb2 gene plays a role in the anaphylactoid reactions induced by Houttuynia cordata injection. Journal of Ethnopharmacology (2022)3. Mast Cell Specific Receptor Mrgprb2 Regulating Experimental Colitis is Associated with the Microbiota-Gut-Brain Axis. J Inflamm Res (2022) |