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BALB/cJGpt
BALB/cJGpt|Strain NO.N000020
Inbred strain
Product Type:
Live Mouse
Frozen Embryo
Quantity:
-
+
Sex:
Male
Female
Age:
1 weeks
2 weeks
3 weeks
4 weeks
5 weeks
6 weeks
7 weeks
8 weeks
9 weeks
10 weeks
11 weeks
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13 weeks
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30 weeks
>30 weeks
Genotype:
(BALB/cJGpt近交系)wt/wt
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BASIC INFORMATION
Strain Name:
BALB/cJGpt
Strain Number:
N000020
Official Symbol:
Strain Strategy:
N000020.BALB_cJGpt strain info.pdf
Research Areas:
Inbred line
Strain Background:
[N000020] BALB/cJGpt
Modification Type:
Inbred strain
Inventory Status:
Live,Cryopreserved
Sale Status:
IF (Available for Distribution)
Health Status:
Specific pathogen free (SPF)
Health Report:
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Publications:
1. Prophylactic effects of oral administration of Lactobacillus casei on house dust mite-induced asthma in mice
2. The third generation anti-HER2 chimeric antigen receptor mouse T cells alone or together with anti-PD1 antibody inhibits the growth of mouse breast tumor cells expressing HER2 in vitro and in immune competent mice
3. CRMP2 is a therapeutic target that suppresses the aggressiveness of breast cancer cells by stabilizing RECK
4. Targeting regulator of G protein signaling 1 in tumor-specific T cells enhances their trafficking to breast cancer
5. Creatine promotes cancer metastasis through activation of Smad2/3
6. Iron Doped Carbon Dots based Nanohybrids as a Tetramodal Imaging Agent for Gene Delivery promotion and Photothermal-Chemodynamic Cancer Synergistic Theranostics
7. Circ-0005105 activates COL11A1 by targeting miR-20a-3p to promote pancreatic ductal adenocarcinoma progression
8. Polymer-directed supramolecular assembly of photosensitizers: Evocation of photothermal effect and highly efficient loading of disulfiram for chemo-phototherapy of cancer
9. PPARγ mediates the anti-epithelial-mesenchymal transition effects of FGF1ΔHBS in chronic kidney diseases via inhibition of TGF-β1/SMAD3 signaling
10. Transdermal delivery of heparin using low-frequency sonophoresis in combination with sponge spicules for venous thrombosis treatment
11. Self-Assembly of a Multifunction DNA Tetrahedron for Effective Delivery of Aptamer PL1 and Pcsk9 siRNA Potentiate Immune Checkpoint Therapy for Colorectal Cancer
12. Discovery and Optimization of a Synthetic Class of Nectin-4-Targeted CD137 Agonists for Immuno-oncology
13. Engineering micro oxygen factories to slow tumour progression via hyperoxic microenvironments
14. Targeting cathepsin B by cycloastragenol enhances antitumor immunity of CD8 T cells via inhibiting MHC-I degradation
15. Magnetic Fields Affect Alcoholic Liver Disease by Liver Cell Oxidative Stress and Proliferation Regulation
16. Controlled intracellular aggregation of magnetic particles improves permeation and retention for magnetic hyperthermia promotion and immune activation
17. EHBP1L1 Drives Immune Evasion in Renal Cell Carcinoma through Binding and Stabilizing JAK1
18. ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy
19. Stimuli-responsive heparin-drug conjugates co-assembled into stable nanomedicines for cancer therapy
20. Design of a novel chimeric peptide via dual blockade of CD47/SIRPalpha and PD-1/PD-L1 for cancer immunotherapy
21. Lighting up metastasis process before formation of secondary tumor by phosphorescence imaging
22. LncRNA UCA1 Participates in De Novo Synthesis of Guanine Nucleotides in Bladder Cancer by Recruiting TWIST1 to Increase IMPDH1/2
23. FGF19-Induced Inflammatory CAF Promoted Neutrophil Extracellular Trap Formation in the Liver Metastasis of Colorectal Cancer
24. Glutathione-Exhausting Nanoprobes for NIR-II Fluorescence Imaging-Guided Surgery and Boosting Radiation Therapy Efficacy via Ferroptosis in Breast Cancer
25. Near-Infrared Persistent Luminescence Nanoprobe for Ultrasensitive Image-Guided Tumor Resection
26. Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease
27. Gastric Acid-Responsive ROS Nanogenerators for Effective Treatment of Helicobacter pylori Infection without Disrupting Homeostasis of Intestinal Flora
28. The super-enhancer-driven lncRNA LINC00880 acts as a scaffold between CDK1 and PRDX1 to sustain the malignance of lung adenocarcinoma
29. Zhoushi Qiling decoction inhibits proliferation of human prostate cancer cells through IL6/STAT3 pathway
30. Appendectomy Mitigates Coxsackievirus B3−Induced Viral Myocarditis
31. B4GALNT1 promotes hepatocellular carcinoma stemness and progression via integrin α2β1-mediated FAK and AKT activation
32. Cantharidin induces apoptosis of human triple negative breast cancer cells through mir-607-mediated downregulation of EGFR
33. Knockdown of ANXA10 induces ferroptosis by inhibiting autophagy-mediated TFRC degradation in colorectal cancer
34. PDCD2 as a prognostic biomarker in glioma correlates with malignant phenotype
35. Enhanced Chemo-Immunotherapy Strategy Utilizing Injectable Thermosensitive Hydrogel for The Treatment of Diffuse Peritoneal Metastasis in Advanced Colorectal Cancer
36. Essential oil extracted from Quzhou Aurantii Fructus prevents acute liver failure through inhibiting lipopolysaccharide-mediated inflammatory response
37. Long-term assessment of cutaneous inflammation and treatment using optical resolution photoacoustic microscopy
38. SARS-CoV-2 mRNA vaccine requires signal peptide to induce antibody responses
39. Engineered oncolytic bacteria HCS1 exerts high immune stimulation and safety profiles for cancer therapy
40. Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine
41. Relationship between circadian rhythm-related genes and extracellular matrix: implications for sleep deprivation
42. Identification of tanshinone I as cap-dependent endonuclease inhibitor with broad-spectrum antiviral effect
43. Blocking MyD88 signaling with MyD88 inhibitor prevents colitis-associated colorectal cancer development by maintaining colonic microbiota homeostasis
44. Carbon dot nanozymes as free radicals scavengers for the management of hepatic ischemia-reperfusion injury by regulating the liver inflammatory network and inhibiting apoptosis
45. Decitabine/paclitaxel co-delivery systems modified with anti-PD-L1 antibodies mediate chemoimmunotherapy for Triple negative breast cancer
46. Dual‑directional effect of vinorelbine combined with cisplatin or fluorouracil on tumor growth and metastasis in metronomic chemotherapy in breast cancer
47. Empagliflozin alleviates the development of autoimmune myocarditis via inhibiting NF-kappaB-dependent cardiomyocyte pyroptosis
48. Nano-modulators with the function of disrupting mitochondrial Ca(2+) homeostasis and photothermal conversion for synergistic breast cancer therapy
49. PD-L1 blockade TAM-dependently potentiates mild photothermal therapy against triple-negative breast cancer
50. Retinoic acid-inducible gene-1 knockdown induces immature properties in dendritic cells and prolongs the survival time of allograft mice
51. TBX15 facilitates malignant progression of glioma by transcriptional activation of TXDNC5
52. Dock5 Deficiency Promotes Proteinuric Kidney Diseases via Modulating Podocyte Lipid Metabolism
53. MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning
54. BATF and BATF3 deficiency alters CD8+ effector/exhausted T cells balance in skin transplantation
55. LncRNA CHROMR/miR-27b-3p/MET axis promotes the proliferation, invasion and contributes to rituximab resistance in diffuse large B-cell lymphoma
56. Usenamine A triggers NLRP3 caspase-1 GSDMD-mediated pyroptosis in lung adenocarcinoma by targeting the DDX3X SQSTM1 axis
57. Establishment of an Inhalation Administration Noninvasive Murine Model for Rapidly Testing Drug Activity against Mycobacterium tuberculosis
58. CBX2 Deletion Suppresses Growth and Metastasis of Colorectal Cancer by Mettl3-p38/ERK MAPK Signalling Pathway
59. AMXT-1501 targets membrane phospholipids against Gram-positive and -negative multidrug-resistant bacteria
60. LncRNA CHROMR/miR-27b-3p/MET axis promotes the proliferation, invasion, and contributes to rituximab resistance in diffuse large B-cell lymphoma
61. A Free Amino Acid Diet Alleviates Colorectal Tumorigenesis through Modulating Gut Microbiota and Metabolites
62. Arsenic trioxide augments immunogenic cell death and induces cGAS-STING-IFN pathway activation in hepatocellular carcinoma
63. Biosynthesis of fungus-based oral selenium microcarriers for radioprotection and immuno-homeostasis shaping against radiation-induced heart disease
64. Intranasal PAMAM-G3 scavenges cell-free DNA attenuating the allergic airway inflammation
65. The role of USP7-YY1 interaction in promoting colorectal cancer growth and metastasis
66. An induced mutation of ABC-transporter component VraF(K84E) contributes to vancomycin resistance and virulence in Staphylococcus aureus strain MW2
67. Biomimetic Hydrogel-Mediated Mechano-Immunometabolic Therapy for Inhibition of ccRCC Recurrence After Surgery
68. Fc-Fc interactions and immune inhibitory effects of IgG4: implications for anti-PD-1 immunotherapies
69. VISTA‐targeted antibody‐drug conjugates exhibit potent antitumor effects on malignant pleural mesothelioma
70. Protective effects of Bacillus amyloliquefaciens-derived nonapeptide in cyclophosphamide-induced immunosuppressed mice
71. Tumour microenvironment programming by an RNA-RNA-binding protein complex creates a druggable vulnerability in IDH-wild-type glioblastoma
72. The rheumatoid arthritis drug auranofin exerts potent anti-lymphoma effect by stimulating TXNRD-mediated ROS generation and inhibition of energy metabolism
73. TORSEL, a 4EBP1-based mTORC1 live-cell sensor, reveals nutrient-sensing targeting by histone deacetylase inhibitors
74. Exposure to microcystin-LR promotes the progression of colitis-associated colorectal cancer by inducing barrier disruption and gut microbiota dysbiosis
75. A High Immune-Related Index with the Suppression of cGAS-STING Pathway is a Key Determinant to Herceptin Resistance in HER2+ Breast Cancer
76. (19)F MRI/CEUS Dual Imaging-Guided Sonodynamic Therapy Enhances Immune Checkpoint Blockade in Triple-Negative Breast Cancer
77. Immunogen characterization reveals an intrinsic hindrance in eliciting neutralizing antibodies against JN.1 variant
78. Role of TSP-1 and its receptor ITGB3 in the renal tubulointerstitial injury of focal segmental glomerulosclerosis
79. alpha-Lactalbumin mRNA-LNP Evokes an Anti-Tumor Effect Combined with Surgery in Triple-Negative Breast Cancer
80. Suppression of pathological neovascularization by anti-Flt1 peptide functionalized DNA tetrahedron
81. Hematopoietic stem and progenitor cell membrane-coated vesicles for bone marrow-targeted leukaemia drug delivery
82. Therapeutic potential of the secreted Kazal-type serine protease inhibitor SPINK4 in colitis
83. Tumor-intrinsic P2RY6 drives immunosuppression by enhancing PGE(2) production
84. Trim21-mediated CCT2 ubiquitination suppresses malignant progression and promotes CD4(+)T cell activation in breast cancer
85. Chromosome instability functions as a potential therapeutic reference by enhancing chemosensitivity to BCL-XL inhibitors in colorectal carcinoma
86. Preclinical Efficacy of Cap-Dependent and Independent mRNA Vaccines against Bovine Viral Diarrhea Virus-1
87. GelMA loaded with platelet lysate promotes skin regeneration and angiogenesis in pressure ulcers by activating STAT3
88. Exosomal circZNF800 Derived from Glioma Stem-like Cells Regulates Glioblastoma Tumorigenicity via the PIEZO1/Akt Axis
89. Shenqi Sanjie Granules induce Hmox1-mediated ferroptosis to inhibit colorectal cancer
90. 19F MRI/CEUS Dual Imaging‐Guided Sonodynamic Therapy Enhances Immune Checkpoint Blockade in Triple‐Negative Breast Cancer
91. The SIX2/PFN2 feedback loop promotes the stemness of gastric cancer cells
92. Microcystin-LR Regulates Interaction between Tumor Cells and Macrophages via the IRE1α/XBP1 Signaling Pathway to Promote the Progression of Colorectal Cancer
93. Natural agents derived Pickering emulsion enabled by silica nanoparticles with enhanced antibacterial activity against drug-resistant bacteria
94. Apoptotic vesicles (apoVs) derived from fibroblast-converted hepatocyte-like cells effectively ameliorate liver fibrosis
95. Nanobody-Engineered Biohybrid Bacteria Targeting Gastrointestinal Cancers Induce Robust STING-Mediated Anti-Tumor Immunity
96. Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET2
97. Local administration of mRNA encoding cytokine cocktail confers potent anti-tumor immunity
98. Targeting IL-33 reprograms the tumor microenvironment and potentiates antitumor response to anti-PD-L1 immunotherapy
99. FABP4-mediated lipid metabolism promotes TNBC progression and breast cancer stem cell activity
100. Nilotinib boosts the efficacy of anti-PDL1 therapy in colorectal cancer by restoring the expression of MHC-I
101. Photothermal Catalytic Reduction and Bone Tissue Engineering Towards a Three-in-One Therapy Strategy for Osteosarcoma
102. Efficacy and safety evaluation of cross-reactive Fibroblast activation protein scFv-based CAR-T cells
103. Enhanced tumor targeting and penetration of fluorophores via iRGD peptide conjugation: a strategy for the precision targeting of lung cancer
104. Metal-phenolic-network-coated gold nanoclusters for enhanced photothermal/chemodynamic/immunogenic cancer therapy
105. Multiplex antimicrobial activities of the self-assembled amphiphilic polypeptide β nanofiber KF-5 against vaginal pathogens
106. The protective effect and immunomodulatory ability of orally administrated Lacticaseibacillus rhamnosus GG against Mycoplasma pneumoniae infection in BALB/c mice
107. Dynamic transition of Tregs to cytotoxic phenotype amid systemic inflammation in Graves' ophthalmopathy
108. Hypoxia-driven M2-polarized macrophages facilitate the epithelial-mesenchymal transition of glioblastoma via extracellular vesicles
109. Egg White Diet Induces Severe Allergic Enteritis in an Animal Model Driven by Caspase-3 and Gasdermin C-Mediated Mucosal Alarmin Secretion
110. Dyna-vivo-seq unveils cellular RNA dynamics during acute kidney injury via in vivo metabolic RNA labeling-based scRNA-seq
111. Social isolation promotes tumor immune evasion via β2-adrenergic receptor
112. TMED3 promotes prostate cancer via FOXO1a and FOXO3a phosphorylation
113. A protocol for high-throughput screening for small chemicals promoting macrophage-mediated tumor cell phagocytosis in mice
114. OPG promotes lung metastasis by reducing CXCL10 production of monocyte-derived macrophages and decreasing NK cell recruitment
115. Signature of Immune-Related Metabolic Genes Predicts the Prognosis of Hepatocellular Carcinoma
116. Targeting SPP1-orchestrated neutrophil extracellular traps-dominant pre-metastatic niche reduced HCC lung metastasis
117. Targeting G-quadruplex by TMPyP4 for inhibition of colorectal cancer through cell cycle arrest and boosting anti-tumor immunity
118. MTHFD1 Regulates Autophagy to Promote Growth and Metastasis in Colorectal Cancer via the PI3K‐AKT–mTOR Signaling Pathway
119. NOP10 predicts poor prognosis and promotes pancreatic cancer progression
120. Smart Persistent Luminescence Imaging for Early Diagnosis of Drug-Induced Liver Injury
121. Ruthenium (II) Lipid‐Mimics Drive Lipid Phase Separation to Arouse Autophagy‐Ferroptosis Cascade for Photoimmunotherapy
122. Defining the features and structure of neutralizing antibody targeting the silent face of the SARS‐CoV‐2 spike N‐terminal domain
123. A cascade X-ray energy converting approach toward radio-afterglow cancer theranostics
124. Heart ultrasound and biomechanical evaluation of radiation‐induced heart toxicity using transthoracic echocardiogram (TTE) and dynamic mechanical analysis (DMA)
125. Radiation induced liver injury (RILI) evaluation using longitudinal computed tomography (CT) in image‐guided precision murine radiotherapy
126. Target Ligand Separation and Identification of Isoforsythiaside as a Histone Lysine-Specific Demethylase 1 Covalent Inhibitor Against Breast Cancer Metastasis
127. ZNF655 involved in the progression of multiple myeloma via the activation of AKT
128. Early fusion intermediate of ACE2-using coronavirus spike acting as an antiviral target
129. Imbalance of oral microbiome homeostasis: the relationship between microbiota and the occurrence of dental caries
130. Preclinical evaluation of 68Ga‐labeled peptides for targeting CD44 imaging
131. House dust mite induced mucosal barrier dysfunction and type 2 inflammatory responses via the MAPK/AP-1/IL-24 Signaling pathway in allergic rhinitis
132. A Humanized Anti-B7H3× 4-1BB Bispecific Antibody Exerts Potent Antitumor Effects through the Activation of Innate and Adaptive Immunity
133. SQYC formula improves the efficacy of PD-1 monoclonal antibodies in MSS colorectal cancer by regulating dendritic cell mitophagy via the PINK1-Parkin pathway
134. A pH-responsive magnetic-controlled nanocomposite for precise and efficient vancomycin delivery in treating prosthetic joint infections
135. Synergistic Synbiotic-Containing Lactiplantibacillus plantarum and Fructo-Oligosaccharide Alleviate the Allergenicity of Mice Induced by Soy Protein
136. METTL3 Potentiates M2 Macrophage‐Driven MMT to Aggravate Renal Allograft Fibrosis via the TGF‐β1/Smad3 Pathway
137. Targeting MAPK14 by Lobeline Upregulates Slurp1‐Mediated Inhibition of Alternative Activation of TAM and Retards Colorectal Cancer Growth
138. A humanized anti-MSLN× 4-1BB bispecific antibody exhibits potent antitumour activity through 4-1BB signaling activation and fc function without systemic toxicity
139. MORF4L2 induces immunosuppressive microenvironment and immunotherapy resistance through GRHL2/MORF4L2/H4K12Ac/CSF1 axis in triple-negative breast cancer
140. Gut–liver translocation of pathogen Klebsiella pneumoniae promotes hepatocellular carcinoma in mice
141. S100A8/A9 Promotes Dendritic Cell–Mediated Th17 Cell Response in Sjögren's Dry Eye Disease by Regulating the Acod1/STAT3 Pathway
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