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DBA/1JGpt

DBA/1JGpt|Strain NO.N000219

Inbred strain

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BASIC INFORMATION
Strain Name: DBA/1JGpt
Strain Number: N000219
Official Symbol:
Strain Strategy: N000219.DBA_1JGpt strain info.pdf
Research Areas: Inbred line
Strain Background: [N000219] DBA/1JGpt
Modification Type: Inbred strain
Inventory Status: Live,Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. The mechanism of Chinese herbal formula HQT in the treatment of rheumatoid arthritis is related to its regulation of lncRNA uc.477 and miR‐19b. Journal of Leukocyte Biology (2020)2. MicroRNA-26b-5p alleviates murine collagen-induced arthritis by modulating Th17 cell plasticity. Cellular Immunology (2021)3. PU. 1 promotes development of rheumatoid arthritis via repressing FLT3 in macrophages and fibroblast-like synoviocytes. Annals of the Rheumatic Diseases (2022)4. Dual-Triggered Near-Infrared Persistent Luminescence Nanoprobe for Autofluorescence-Free Imaging-Guided Precise Therapy of Rheumatoid Arthritis. Adv Sci (Weinh) (2022)5. PU.1 promotes development of rheumatoid arthritis via repressing FLT3 in macrophages and fibroblastlike synoviocytes. ANNALS OF THE RHEUMATIC DISEASES (2023)6. Multi-organ single-cell analysis reveals an on/off switch system with potential for personalized treatment of immunological diseases. Cell Reports Medicine (2023)7. TNF-alpha-Induced KAT2A Impedes BMMSC Quiescence by Mediating Succinylation of the Mitophagy-Related Protein VCP. Adv Sci (2024)8. Apoptotic extracellular vesicles restore homeostasis of the articular microenvironment for the treatment of rheumatoid arthritis. Bioact Mater (2024)9. Administration of Liposomal-Based Pde3b Gene Therapy Protects Mice Against Collagen-Induced Rheumatoid Arthritis via Modulating Macrophage Polarization. Int J Nanomedicine (2024)10. Synergistic rheumatoid arthritis therapy by interrupting the detrimental feedback loop to orchestrate hypoxia M1 macrophage polarization using an enzyme-catalyzed nanoplatform. Bioact Mater (2024)11. Positive feedback loop PU.1-IL9 in Th9 promotes rheumatoid arthritis development. Annals of the Rheumatic Diseases (2024)12. Generation of cytotoxic aptamers specifically targeting fibroblast-like synoviocytes by CSCT-SELEX for treatment of rheumatoid arthritis. Annals of the Rheumatic Diseases (2024)13. Rhaponticin Alleviates Collagen-induced Arthritis by Inhibiting NLRP3/GSDMD-mediated Neutrophil Extracellular Traps. Inflammation (2024)14. Targeting macrophage polarization by inhibiting Pim2 alleviates inflammatory arthritis via metabolic reprogramming. Cellular & molecular immunology (2025)15. Polysaccharide Nanoadjuvants Engineered via Phenotype-Specific Nanoprobe-Assisted Phenotypic Screen Reprogram Macrophage Cell Functions for Cancer and Rheumatoid Arthritis Therapy. ACS Nano (2025)16. NaHS@Cy5@MS@SP nanoparticles improve rheumatoid arthritis by inactivating the Hedgehog signaling pathway through sustained and targeted release of H2S into the synovium. J Nanobiotechnology (2025)17. Dual-driven selenium Janus single-atom nanomotors for autonomous regulating mitochondrial oxygen imbalance to catalytic therapy of rheumatoid arthritis. Redox Biol (2025)18. Therapeutic Potential of Lipid Nanoparticle-Encapsulated CD19-Targeting mRNAs in Lupus and Rheumatoid Arthritis. Adv Sci (Weinh) (2025)19. Baicalein prevents pregnancy loss by maintaining regulatory T cell activation through inhibition of the TLR4/NF-κB signaling pathway. Placenta (2025)20. Generation of tolerogenic antigen-presenting cells in vivo via the delivery of mRNA encoding PDL1 within lipid nanoparticles. Nat Biomed Eng (2025)21. Inflammatory macrophage-derived itaconate inhibits DNA demethylase TET2 to prevent excessive osteoclast activation in rheumatoid arthritis. Bone research (2025)22. Engineered Spirulina platensis for treating rheumatoid arthritis and restoring bone homeostasis. Nature communications (2025)23. Polypyrrole-ferric phosphate-methotrexate nanoparticles enhance apoptosis/ferroptosis of M1 macrophages via autophagy blockage for rheumatoid arthritis treatment. Journal of nanobiotechnology (2025)