C57BL/6JGpt-Ncor1em1Cflox/Gpt
Ncor1-flox|Strain NO.T007978
Conditional knockout (cKO)
![](https://oss.gempharmatech.com/upload/20221109/detail-page2_06.jpg)
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BASIC INFORMATION
Strain Name: | C57BL/6JGpt-Ncor1em1Cflox/Gpt |
Strain Number: | T007978 |
Official Symbol: | Ncor1 |
Strain Strategy: | T007978.Ncor1 Cas9-CKO Strategy-EN.pdf |
Official Full Name: | nuclear receptor co-repressor 1 |
Also Known As: | 5730405M06Rik,A230020K14Rik,N-CoR,RIP13,Rxrip13,mKIAA1047 |
NCBI Number: | 20185 |
MGI Number: | 1349717 |
Chromosome: | 11 |
Distance Between Two Loxps: | 1500bp |
Research Areas: | Metabolic research,Developmental Biology,immune system,integument,cardiovascular system,nervous system,Signal Transduction,Muscle ,adipose tissue,Cell Proliferation,Cytoskeleton,DNA transcription,digestive/alimentary system,Protein metabolism,Glucose metabolism,liver/biliary system,Physiological system,endocrine/exocrine glands,homeostasis/metabolism,behavior/neurological,cell differentiation,Cell biology,Molecular biology,cellular,embryo,growth/size/body,hematopoietic system,mortality/aging,Lipid Metabolism,cell nucleus,DNA binding protein,Regulation of enzyme activity |
Strain Background: | [N000013] C57BL/6JGpt |
Modification Type: | Conditional knockout (cKO) |
Genotyping Protocols: | T007978.Ncor1 Genotyping Protocol(CKO).pdf |
Inventory Status: | Cryopreserved |
Sale Status: | IF (Available for Distribution) |
Health Status: | Specific pathogen free (SPF) |
Publications: | 1. Hepatic NCoR1 deletion exacerbates alcohol-induced liver injury in mice by promoting CCL2-mediated monocyte-derived macrophage infiltration |
Gene Family: | Myb/SANT domain containingNCoR/SMRT transcriptional repression complex subunitsProtein phosphatase 1 regulatory subunits |