C57BL/6JGpt-Ncor1em1Cflox/Gpt
Ncor1-flox|Strain NO.T007978
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
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- Age:
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BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Ncor1em1Cflox/Gpt |
| Strain Number: | T007978 |
| Official Symbol: | Ncor1 |
| Strain Strategy: | T007978.Ncor1 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | nuclear receptor co-repressor 1 |
| Also Known As: | 5730405M06Rik,A230020K14Rik,N-CoR,RIP13,Rxrip13,mKIAA1047 |
| NCBI Number: | 20185 |
| MGI Number: | 1349717 |
| Chromosome: | 11 |
| Distance Between Two Loxps: | 1500bp |
| Research Areas: | Metabolic research,Developmental Biology,immune system,integument,cardiovascular system,nervous system,Signal Transduction,Muscle ,adipose tissue,Cell Proliferation,Cytoskeleton,DNA transcription,digestive/alimentary system,Protein metabolism,Glucose metabolism,liver/biliary system,Physiological system,endocrine/exocrine glands,homeostasis/metabolism,behavior/neurological,cell differentiation,Cell biology,Molecular biology,cellular,embryo,growth/size/body,hematopoietic system,mortality/aging,Lipid Metabolism,cell nucleus,DNA binding protein,Regulation of enzyme activity |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T007978.Ncor1 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Hepatic NCoR1 deletion exacerbates alcohol-induced liver injury in mice by promoting CCL2-mediated monocyte-derived macrophage infiltration |
| Gene Family: | Myb/SANT domain containingNCoR/SMRT transcriptional repression complex subunitsProtein phosphatase 1 regulatory subunits |