C57BL/6JGpt-Creg1em1Cflox/Gpt

Creg1-flox|Strain NO.T008634

Conditional knockout (cKO)

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BASIC INFORMATION
Strain Name: C57BL/6JGpt-Creg1em1Cflox/Gpt
Strain Number: T008634
Official Symbol: Creg1
Strain Strategy: T008634.Creg1 Cas9-CKO Strategy-EN.pdf
Official Full Name: cellular repressor of E1A-stimulated genes 1
Also Known As: AA755314,Creg
NCBI Number: 433375
MGI Number: 1344382
Chromosome: 1
Distance Between Two Loxps: 1735bp
Research Areas: Metabolic research,homeostasis/metabolism,Developmental Biology,growth/size/body,Physiological system,cardiovascular system,Muscle ,digestive/alimentary system,liver/biliary system,Cell biology,cellular,Molecular biology,DNA transcription
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Conditional knockout (cKO)
Genotyping Protocols: T008634.Creg1 Genotyping Protocol(CKO).pdf
Inventory Status: Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Hepatocyte-specific deletion of cellular repressor of E1A-stimulated genes 1 exacerbates alcohol-induced liver injury by activating stress kinases. International Journal of Biological Sciences (2022)2. CREG1 deficiency impaired myoblast differentiation and skeletal muscle regeneration. J Cachexia Sarcopenia Muscle (2024)