C57BL/6JGpt-Hmgcs2em2Cd1239/Gpt
Hmgcs2-KO|Strain NO.T004234
Knockout (KO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Hmgcs2em2Cd1239/Gpt |
| Strain Number: | T004234 |
| Official Symbol: | Hmgcs2 |
| Strain Strategy: | T004234.Hmgcs2 Cas9-KO Strategy-EN.pdf |
| Official Full Name: | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 |
| Also Known As: | 1300002P16,mHS |
| NCBI Number: | 15360 |
| MGI Number: | 101939 |
| Chromosome: | 3 |
| Deletion (size): | -1239bp |
| Research Areas: | skeleton,Glucose metabolism,Mitochondrial research,homeostasis/metabolism,Lipid Metabolism,Organelles membrane,transferase |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T004234.Hmgcs2 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. LONP1 targets HMGCS2 to protect mitochondrial function and attenuate chronic kidney disease. EMBO Mol Med (2023) |