C57BL/6JGpt-Ptpn11em1Cflox/Gpt
Ptpn11-flox|Strain NO.T010047
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Ptpn11em1Cflox/Gpt |
| Strain Number: | T010047 |
| Official Symbol: | Ptpn11 |
| Strain Strategy: | T010047.Ptpn11 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | protein tyrosine phosphatase, non-receptor type 11 |
| Also Known As: | 2700084A17Rik,AW536184,PTP1D,PTP2C,SAP-2,SH-PTP2,SH-PTP3,SHP-2,Shp2,Syp |
| NCBI Number: | 19247 |
| MGI Number: | 99511 |
| Chromosome: | 5 |
| Distance Between Two Loxps: | 9100bp |
| Research Areas: | Metabolic research,Developmental Biology,immune system,integument,cardiovascular system,Tumor research,nervous system,Signal Transduction,skeleton,vision/eye,hearing/ear,Muscle ,respiratory system,adipose tissue,Cytoskeleton,reproductive system,digestive/alimentary system,Protein metabolism,liver/biliary system,Mitochondrial research,Physiological system,endocrine/exocrine glands,homeostasis/metabolism,behavior/neurological,cell differentiation,Cell biology,Molecular biology,cellular,craniofacial ,embryo,growth/size/body,hematopoietic system,limbs/digits/tail,mortality/aging,pigmentation,Cell localization,Lipid Metabolism,cell nucleus,hydrolytic enzyme,Noonan Syndrome |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T010047.Ptpn11 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Tyrosine phosphatase SHP2 exacerbates psoriasis-like skin inflammation in mice via ERK5-dependent NETosis |
| Gene Family: | Protein tyrosine phosphatases non-receptor typeSH2 domain containing |