C57BL/6JGpt-Lifrem1Cflox/Gpt
Mouse Model: Lifr-flox
Strain Number: T007819
Conditional knockout (cKO)
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- Quantity: - +
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GemPharmatech Offers the World’s Largest Knockout and Conditional Knockout Library
With over 25,000 mouse models available and thousands of new strains developed annually, GemPharmatech has built the world’s largest knockout and conditional knockout resource library. Every model is generated using cutting-edge gene editing and validated at the genomic level to ensure reliability. Choosing GemPharmatech means more than acquiring a mouse model, it means partnering with a global leader committed to scientific rigor, competitive pricing, and timely delivery of the mice models your research requires.
| Strain Name: | C57BL/6JGpt-Lifrem1Cflox/Gpt |
| Strain Number: | T007819 |
| Official Symbol: | Lifr |
| Strain Strategy: | T007819.Lifr Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | LIF receptor alpha |
| Also Known As: | A230075M04Rik,AW061234,LIF |
| NCBI Number: | 16880 |
| MGI Number: | 96788 |
| Chromosome: | 15 |
| Distance Between Two Loxps: | 1263bp |
| Research Areas: | Metabolic research,Developmental Biology,immune system,nervous system,Signal Transduction,skeleton,Cell Proliferation,Cell death,reproductive system,digestive/alimentary system,liver/biliary system,renal/urinary system,Physiological system,endocrine/exocrine glands,homeostasis/metabolism,cell differentiation,Cell biology,Molecular biology,cellular,embryo,growth/size/body,hematopoietic system,limbs/digits/tail,mortality/aging,Organelles membrane |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T007819.Lifr Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Hexosamine biosynthesis dysfunction-induced LIFR N-glycosylation deficiency exacerbates steatotic liver ischemia/reperfusion injury. Metabolism (2025) |
| Gene Family: | CD moleculesFibronectin type III domain containingMicroRNA protein coding host genes |
Extend the Value of Your Mouse Models with Integrated Preclinical Services
GemPharmatech not only provides access to advanced genetically engineered mouse models but also offers comprehensive preclinical research services to help you maximize their value. Our scientific team can support your studies from model construction through phenotype validation and pharmacology testing, ensuring that every experiment is designed for translational relevance. By pairing this conditional knockout model with GemPharmatech’s preclinical services, you gain an integrated workflow that accelerates discovery, reduces risk, and produces robust, actionable data.