C57BL/6JGpt-Alkbh5em1Cflox/Gpt
Alkbh5-flox|Strain NO.T008382
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
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BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Alkbh5em1Cflox/Gpt |
| Strain Number: | T008382 |
| Official Symbol: | Alkbh5 |
| Strain Strategy: | Log in to read more |
| Official Full Name: | alkB homolog 5, RNA demethylase |
| Also Known As: | AW050020,AW215868,Abh5,E130207K11,Ofoxd |
| NCBI Number: | 268420 |
| MGI Number: | 2144489 |
| Chromosome: | 11 |
| Distance Between Two Loxps: | 15183bp |
| Research Areas: | Developmental Biology,cell differentiation,Physiological system,reproductive system,endocrine/exocrine glands,Cell biology,cellular,Cell localization,Golgi apparatus,cell nucleus,Molecular biology,oxidordeuctase |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | Log in to read more |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Inhibition of ALKBH5 attenuates I/R-induced renal injury in male mice by promoting Ccl28 m6A modification and increasing Treg recruitment. Nature Communications (2023)2. Liver ALKBH5 regulates glucose and lipid homeostasis independently through GCGR and mTORC1 signaling. Science (2025) |
| Gene Family: | Alkylation repair homologs |