C57BL/6JGpt-Atf4em1Cflox/Gpt
Atf4-flox|Strain NO.T008417
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Atf4em1Cflox/Gpt |
| Strain Number: | T008417 |
| Official Symbol: | Atf4 |
| Strain Strategy: | T008417.Atf4 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | activating transcription factor 4 |
| Also Known As: | Atf-4,C/ATF,CREB2,TAXREB67 |
| NCBI Number: | 11911 |
| MGI Number: | 88096 |
| Chromosome: | 15 |
| Distance Between Two Loxps: | 2196bp |
| Research Areas: | Metabolic research,Developmental Biology,integument,cardiovascular system,nervous system,Signal Transduction,skeleton,vision/eye,Muscle ,adipose tissue,Cell death,Cytoskeleton,DNA transcription,reproductive system,digestive/alimentary system,liver/biliary system,Physiological system,endocrine/exocrine glands,homeostasis/metabolism,Cell biology,Molecular biology,cellular,craniofacial ,embryo,growth/size/body,hematopoietic system,mortality/aging,Cell localization,cell nucleus,Organelles membrane,DNA binding protein |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T008417.Atf4 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4 |
| Gene Family: | Basic leucine zipper proteins |