C57BL/6JGpt-Lepem1Cflox/Gpt
Lep-flox|Strain NO.T009981
Conditional knockout (cKO)
![](https://oss.gempharmatech.com/upload/20221109/detail-page2_06.jpg)
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BASIC INFORMATION
Strain Name: | C57BL/6JGpt-Lepem1Cflox/Gpt |
Strain Number: | T009981 |
Official Symbol: | Lep |
Strain Strategy: | T009981.Lep Cas9-CKO Strategy-EN.pdf |
Official Full Name: | leptin |
Also Known As: | ob,obese |
NCBI Number: | 16846 |
MGI Number: | 104663 |
Chromosome: | 6 |
Distance Between Two Loxps: | 7522bp |
Research Areas: | Metabolic research,adipose tissue,Protein metabolism,Glucose metabolism,homeostasis/metabolism,Lipid Metabolism,Developmental Biology,cell differentiation,embryo,growth/size/body,mortality/aging,immune system,Tumor research,nervous system,vision/eye,behavior/neurological,Physiological system,integument,cardiovascular system,skeleton,Muscle ,respiratory system,reproductive system,digestive/alimentary system,liver/biliary system,renal/urinary system,endocrine/exocrine glands,hematopoietic system,limbs/digits/tail,Cell biology,Cell Proliferation,Cell death,cellular,Cell localization,Molecular biology,Signal Transduction,DNA transcription,DNA binding protein |
Strain Background: | [N000013] C57BL/6JGpt |
Modification Type: | Conditional knockout (cKO) |
Genotyping Protocols: | T009981.Lep Genotyping Protocol(CKO).pdf |
Inventory Status: | Cryopreserved |
Sale Status: | IF (Available for Distribution) |
Health Status: | Specific pathogen free (SPF) |
Publications: | 1. Mitochondrial glycerol 3-phosphate dehydrogenase deficiency exacerbates lipotoxic cardiomyopathy |
Gene Family: | Neuropeptides |