C57BL/6JGpt-Dhcr24em1Cflox/Gpt
Dhcr24-flox|Strain NO.T008998
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
- Sex:
- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Dhcr24em1Cflox/Gpt |
| Strain Number: | T008998 |
| Official Symbol: | Dhcr24 |
| Strain Strategy: | T008998. Dhcr24 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | 24-dehydrocholesterol reductase |
| Also Known As: | 2310076D10Rik,5830417J06Rik,mKIAA0018 |
| NCBI Number: | 74754 |
| MGI Number: | 1922004 |
| Chromosome: | 4 |
| Distance Between Two Loxps: | 1798bp |
| Research Areas: | Metabolic research,adipose tissue,Protein metabolism,homeostasis/metabolism,Lipid Metabolism,Developmental Biology,growth/size/body,mortality/aging,nervous system,behavior/neurological,Physiological system,integument,reproductive system,endocrine/exocrine glands,Cell biology,Cell Proliferation,Cell death,Cytoskeleton,cellular,endoplasmic reticulum,Golgi apparatus,cell nucleus,Molecular biology,Signal Transduction,oxidordeuctase |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T008998.Dhcr24 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. DHCR24 insufficiency promotes vascular endothelial cell senescence and endothelial dysfunction via inhibition of Caveolin-1/ERK signaling. THE JOURNALS OF GERONTOLOGY SERIES A (2024) |