C57BL/6JGpt-Fut2em1Cflox/Gpt
Fut2-flox|Strain NO.T008839
Conditional knockout (cKO)
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BASIC INFORMATION
Strain Name: | C57BL/6JGpt-Fut2em1Cflox/Gpt |
Strain Number: | T008839 |
Official Symbol: | Fut2 |
Strain Strategy: | T008839.Fut2 Cas9-CKO Strategy-EN.pdf |
Official Full Name: | fucosyltransferase 2 |
NCBI Number: | 14344 |
MGI Number: | 109374 |
Chromosome: | 7 |
Distance Between Two Loxps: | 8600bp |
Research Areas: | Protein metabolism,Glucose metabolism,Lipid Metabolism,immune system,reproductive system,digestive/alimentary system,Golgi apparatus,transferase |
Strain Background: | [N000013] C57BL/6JGpt |
Modification Type: | Conditional knockout (cKO) |
Genotyping Protocols: | T008839.Fut2 Genotyping Protocol(CKO).pdf |
Inventory Status: | Cryopreserved |
Sale Status: | IF (Available for Distribution) |
Health Status: | Specific pathogen free (SPF) |
Publications: | 1. Intestinal epithelium-specific Fut2 deficiency promotes colorectal cancer through down-regulating fucosylation of MCAM2. FUT2 inhibits the EMT and metastasis of colorectal cancer by increasing LRP1 fucosylation |
Gene Family: | Fucosyltransferases |