C57BL/6JGpt-Fut2em1Cflox/Gpt
Fut2-flox|Strain NO.T008839
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
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BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Fut2em1Cflox/Gpt |
| Strain Number: | T008839 |
| Official Symbol: | Fut2 |
| Strain Strategy: | T008839.Fut2 Cas9-CKO Strategy-EN.pdf |
| Official Full Name: | fucosyltransferase 2 |
| NCBI Number: | 14344 |
| MGI Number: | 109374 |
| Chromosome: | 7 |
| Distance Between Two Loxps: | 8600bp |
| Research Areas: | Protein metabolism,Glucose metabolism,Lipid Metabolism,immune system,reproductive system,digestive/alimentary system,Golgi apparatus,transferase |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | T008839.Fut2 Genotyping Protocol(CKO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Intestinal epithelium-specific Fut2 deficiency promotes colorectal cancer through down-regulating fucosylation of MCAM2. FUT2 inhibits the EMT and metastasis of colorectal cancer by increasing LRP1 fucosylation |
| Gene Family: | Fucosyltransferases |